A Phase II Study of Observation in Favorable Low-Grade Glioma and Phase III Study of Radiation With or Without PCV Chemotherapy in Unfavorable Low-Grade Glioma
Principal Investigator
Edward Shaw, MD
Status
Terminated
Date Opened To Accrual
October 31 1998
Date Closed to Accrual
June 27 2002
Date of Study Termination
May 14 2018
Disease Site
Brain [BN]
Other
Phase
II/III
Developmental Therapeutics
No
Primary Objective
To identify the overall (and relapse-free) survival of low-risk adult patients with supratentorial LGG (<40 years old who undergo gross total resection of a WHO grade II astrocytoma, oligodendroglioma, or mixed oligoastrocytoma) who are observed postoperatively.
Data Collection Notice:
Data for this trial is being collected via the NRG/RTOG Data Center.
Patient Population
Histologic proof of supratentorial WHO grade II astrocytoma, oligodendroglioma, or oligoastrocytoma confirmed by central pathology review prior to randomization.
Target Accrual
252
Patient Study Webpage
There is no available patient study webpage available for this trial at this time.