A Phase III Trial Of Accelerated Whole Breast Irradiation With Hypofractionation Plus Concurrent Boost Versus Standard Whole Breast Irradiation Plus Sequential Boost For Early-Stage Breast Cancer
Principal Investigator
Frank Vicini, MD
Status
Closed to Accrual
Date Opened To Accrual
May 24 2011
Date Closed to Accrual
June 20 2014
Disease Site
Breast [BR]
Breast
Phase
III
Developmental Therapeutics
No
Primary Objective
To determine whether an accelerated course of hypofractionated WBI including a concomitant boost to the tumor bed in 15 fractions following lumpectomy will prove to be non-inferior in local control to a regimen of standard WBI with a sequential boost following lumpectomy for early-stage breast cancer patients.
Patient Population
pStage 0, I, II Breast Cancer resected by lumpectomy
pStage 0, I,II Breast Cancer resected by lumpectomy that followed neoadjuvant systemic therapy
Target Accrual
2312
Patient Study Webpage
There is no available patient study webpage available for this trial at this time.