NRG-BN014

Open to Accrual

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A Phase III Randomized Clinical Trial of Proton Craniospinal Irradiation Versus Involved-Field Radiotherapy for Patients With Breast Cancer or Non-Small Cell Lung Cancer Leptomeningeal Metastasis (RADIATE-LM)

Principal Investigator

Jonathan Yang, MD, PhD,

Status

Open to Accrual

Date Opened To Accrual

November 21 2024

Disease Site

Brain [BN]

Other

Phase

III

Developmental Therapeutics

Primary Objective

To compare overall survival (OS) between proton craniospinal irradiation (pCSI) and involved-field radiotherapy (IFRT) in patients with breast cancer or non-small cell lung cancer (NSCLC) leptomeningeal metastasis.

Patient Population

Patients with breast cancer or non-small cell lung cancer leptomeningeal metastasis

Target Accrual

144

Protocol Documents

Available via the National Cancer Institute (NCI) Cancer Trials Support Unit (CTSU) website.

Patient Study Webpage

There is no available patient study webpage available for this trial at this time.

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