A Phase II Trial Evaluating Cisplatin (NSC #119875) and Gemcitabine (NSC #613327) Concurrent with Intensity-Modulated Radiation Therapy (IMRT) in the Treatment of Locally Advanced Squamous Cell Carcinoma of the Vulva
Principal Investigator
Neil Horowitz, MD
Status
Terminated
Date of Study Termination
June 01 2024
Disease Site
Gynecologic [GY]
Other
Phase
II
Developmental Therapeutics
No
Primary Objective
To determine the efficacy of cisplatin, gemcitabine, and Intensity-Modulated Radiation Therapy (IMRT) in achieving a complete pathologic response when used for the primary treatment of locally-advanced squamous cell carcinoma of the vulva.
Patient Population
Patients with locally-advanced, previously untreated squamous cell T2 or T3 primary vulvar tumors (N0-3,M0) not amenable to surgical resection by standard radical vulvectomy
Target Accrual
49
Patient Study Webpage
There is no available patient study webpage available for this trial at this time.