NRG-BN014 is a clinical study for people with breast cancer or non-small cell lung cancer that has spread to the cerebrospinal fluid-filled space that surrounds the brain and spinal cord, also called leptomeningeal metastasis (LM). This study will compare two types of radiotherapy, proton craniospinal radiation therapy and photon involved-field radiation therapy. Proton craniospinal radiation therapy is a type of radiotherapy that uses proton particles to deliver radiation, in this case, to your entire cerebrospinal fluid-filled space surrounding your brain and spinal cord where the LM is located. Photon involved-field radiation therapy uses x-rays to treat specific areas where LM is present to relieve and/or prevent symptoms. Researchers want to know if using proton craniospinal radiation therapy to treat the entire cerebrospinal fluid-filled space is better, worse, or the same as the usual treatment (photon involved-field radiation therapy) for people with your type of cancer.
More information about this particular study is located on ClinicalTrials.gov
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Below, you can find FAQs about clinical research and this particular clinical trial.
Talk to your insurance provider and make sure that you understand what your insurance pays for and what it doesn’t pay for if you take part in this clinical trial. Also, find out if you need approval from your plan before you can take part in the study.
You will not be paid for taking part in this study.
Doctors and researchers conduct a clinical study, also called a “clinical trial,” to find better ways to prevent, diagnose, or treat an illness. NRG Oncology is supported by the National Cancer Institute (NCI) and runs clinical studies specifically for patients with cancer or to prevent cancer. Most clinical studies test something we know against something we don’t know. In all situations, these studies are strictly evaluated before they are allowed to be offered to any patient. The study is designed to answer the question that we do not know the answer to, so that current and future patients may have better treatments or information than what we currently have. There are different types of clinical studies that might be available for patients. For more information see “Types of Clinical Trials” and “Phases of Clinical Trials”.
Patients who volunteer to take part in a clinical study are followed closely by their health care professionals and members of the research team. For more information see “Research Team Members”.
At NRG Oncology, we focus on conducting clinical studies aimed to improve current cancer care practices and the lives of cancer patients. NRG Oncology partners with more than 1,300 member sites world-wide to research ways to improve treatment standards in the cancer community. Our organization is supported primarily through grants from the National Cancer Institute (NCI) and is one of five research groups in the NCI's National Clinical Trial's Network.